Carvings, December 1, 2025

In the news

I hope that I’m preaching to the choir

        As you know from recent blog posts, the influenza vaccine, though it does not always prevent the flu, is important because it decreases the severity of an infection, likely avoiding hospitalization. You may also recall that an episode of influenza significantly increases the risk of a heart attack or stroke, while the vaccine has just the opposite effect. Another point to emphasize: influenza weakens the immune system, which is the reason why deaths from the flu are almost always due to secondary infection, not viral infection.

                Infectious disease experts warn that this year’s flu season will probably be more severe than most because the current strain is more potent. This is already evident in Australia and the UK. That makes getting the vaccine especially important this winter.

Lifestyle

What hardly anyone knows about exercise.

                The title of this blog might seem somewhat pretentious but the evidence is all around us. Surveys over the years are pretty consistent: about eighty percent of Americans simply do not engage in any form of exercise. An interesting coincidence: eighty present of Americans are overweight or obese. Are they the same eighty percent. Ya think?

                The human body has evolved to require several hours a day of moderately intense physical activity. Before the Industrial Age there was no way around it. Getting to or from anywhere required walking. (Lest you think that riding horseback didn’t require physical activity, be assured that a ride of any distance is a pretty good workout.) Craftsmen used only hand tools; the most mundane household chore required lifting, carrying, chopping, etc..

                Moderately intense physical activity has two major effects: it burns calories and it opens dormant blood vessels. If we use up all the calories we take in there aren’t any left to be turned into fat. That’s obvious but what is not so obvious is that those fat stores are factories (fattories?) for churning out inflammatory chemicals that are the drivers of coronary heart disease, ischemic stroke, type 2 diabetes, cancer and osteoporosis. Another interesting coincidence: none of those conditions exist in pre-industrial societies – not one, except for some cancers!

                When your heart pumps vigorously in the course of intense physical activity, every blood vessel in the body, even those that are “resting”, opens up to accommodate the flow. That ensures that every cell receives oxygen and nutrients and gets rid of accumulated waste products. The ebb and flow of blood also keeps those blood vessels flexible so that they can handle the sudden stress of the kind that might precipitate a heart attack or stroke. 

                Twenty-five percent of the blood that exits the left side of the heart goes to the head, nearly all of it to the brain. Simply put, well-fed brain cells last longer.

                The excuse that I hear most often is “I don’t have time”. I’ll address that issue in the next post.

Carvings September 1, 2025

In the news

Omega-3s and Alzheimer’s Disease

            Omega-3 fats are critical nutrients for every cell in the body, especially those in the brain and eyes. The main natural sources, fish and leafy green vegetables, are lacking in the diets of most people. Now there’s another reason to ensure that you get what you need. A study of more than 800 Alzheimer’s Disease (AD) patients in the UK revealed that women with AD had fewer omega 3s and more saturated fat in their blood than normal individuals. The authors caution that “this still warrants further research” a CYA phrase that seems to be included in so many scientific publications, but it is consistent with hundreds of peer-reviewed articles that show how important omega-3 fats are. A study that I included in my lecture on avoiding dementia about two decades ago revealed that patients with AD had less omega-3 fats in brain tissue than normal persons.

          Alzheimer’s Disease is enormously complex, beginning with the fact that there are several types of this disorder, that at least one form is strongly hereditary, and that not a single drug has been shown to significantly reverse it or to stop it. All the more reason to do what we can with proper nutrition and lifestyle (see the article below) to slow it down.

Lifestyle

What do knitting and playing the piano have in common?

            Neuroscientists have known for decades that mind-engaging activities can stimulate the formation and connectivity of brain cells, thus developing a “cognitive reserve” that delays the progression of age-related brain shrinkage and Alzheimer’s Disease. Two new studies reveal why activities such as knitting and playing the piano are particularly valuable. They both require the use of two hands, advance planning and fine motor movement. (Note that similar activities such as woodworking, painting and model building are similarly beneficial.) The result of the aforementioned nerve cell connectivity is improved memory, better motor skills and a reduction in stress. Specifically, a study of seniors engaged in piano playing showed improvement in areas of the brain that are associated with memory and language. Brain-associated hormones also showed improvement in the knitters. The stress hormone cortisol was reduced while serotonin and dopamine – the latter associated with Parkinson’s Disease – were increased.

          It’s important to emphasize that you can build a cognitive reserve at any age, and the benefits of these activities have been observed even in persons who are already showing symptoms of dementia or Parkinson’s Disease.

          The adage “It’s never too late” takes on new meaning.

Carvings July 15, 2025

In the news

U.S. children’s health going downhill

            A very significant paper was published this month in JAMA, the Journal of the American Medical Association. It is the loudest wake-up call that I have heard yet, warning us of a deadly trend: American children from birth to age 19 years are nearly twice as likely to die as a cohort from 18 other high-income nations. Nearly half (!) – 45.7 percent — have a chronic health condition such as autism, sleep apnea, behavioral disorders and depression, among others. Nearly 21 percent of children are obese. (The figure was 5.2 percent in 1974.) The type 2 diabetes epidemic among children shows no slowing trend.

            It’s frightening to think what this scenario will be like two or three generations from now, knowing that the several causes of these conditions are unlikely to be reversed without severe, draconian regulations that no politician dares to propose. The multiple causes have been staring us in the face for decades but there is no national will to eliminate them.

            A major cause of the decline in our children’s health is the lack of outdoor exercise. Kid power is no longer needed for bicycles, skateboards or scooters. Team sports are over-organized, so that the kids expend minimal energy. A study of PE classes in schools revealed that the students were actually moving for only ten minutes out of an allotted hour.

            Processed foods high in salt and sugar have replaced vegetables. More than half of children are deficient in omega-3 fats that are crucial for brain development and function.

            The recent decision to remove artificial dyes from candy and other forms of junk food will have only a minuscule effect on children’s health. It is junk food, not just its coloring, that should disappear from grocery shelves. That is unlikely and so is the prospect that the nation’s children’s health issues will be reversed in this generation. The only hope is that individuals and their families will follow a healthy lifestyle.

Carvings May 1, 2025

In the news

Your brain on eggs. What does it mean for Alzheimer’s Disease?

            Alzheimer’s Disease (AD) has become a severe burden in the U.S., both financially and emotionally. Six million Americans already suffer from the condition and it is projected to more than double by 2050. It is not only because our population is aging. In my opinion, our diet plays a major role in the development of this debilitating disease. 

            Caveat: this blog addresses only a single nutrient. Many other factors, nutritional, inflammatory, toxicological and social are part of the picture. However, the one discussed here is entirely under our control.

            According to the Framingham Study, a research program that was instituted more than 75 years ago by Harvard Medical School and that carries a stellar reputation in tracking the dietary and lifestyle habits of generations of participants, a low intake of dietary choline is associated with an increased risk of dementia, including Alzheimer’s Disease. It is one of many recent studies that have noted that inverse association. Further, it is becoming evident that the current DRI (Dietary Reference Intake) for choline “may not be optimal for proper brain health and cognition”. (Ref.: Velaquez R et al., Choline as a prevention for Alzheimer’s Disease, Aging 2020 Vol. 12, No 3, p. 2026-270).

            In July 2024 the Rush Memory and Aging Project, involving more than 1,000 subjects, reported that a modest intake of two eggs per week was associated with a decreased risk of Alzheimer’s Disease, and at autopsy, AD patients with a higher egg intake showed fewer changes in the brain than are typical of that disease.

            Although choline is present in many common foods, especially poultry, fish, red meat, eggs, liver, cruciferous vegetables (such as broccoli, kale, Brussels sprouts, etc.), nuts and seeds, the Standard American Diet (S.A.D.) is lacking in almost all of these foods except for red meat. Taking a vitamin supplement won’t help; among several whose labels I examined, none lists choline in the list of ingredients. A solution appears to be the Mediterranean Diet, which includes the best sources of choline and many other nutrients.

            Eggs to the rescue! As noted in recent posts, eggs are among the healthiest foods and contain a generous amount of choline. Cholesterol is a non-issue. Eating two or three eggs every day will not raise your blood cholesterol by a single milligram, unless you eat them with “egg helpers” such as bacon, sausage, ham, hash browns, etc., all of which contain saturated fat, the real cholesterol-drivers. Eggs are excellent sources of protein and vitamins A, B complex, D and E, and several important but lesser-known nutrients.

            The recommendation of the month: Include a veggie omelet in your meal plan at least twice a week. Frozen mixed vegetables make it really easy. Be sure to add a tablespoon of olive oil to the mix. And leave those egg-helpers on the supermarket shelf!

Carvings April 17, 2025

In the news

Synergistic supplements

            I have long argued that a high dose of a single supplement – vitamin, mineral or other – is not a solution to any health problem. Most if not all nutrients interact with each other like the instruments in a symphony orchestra and taking a large amount of any nutrient causes imbalance which can be harmful. On the other hand, we must ensure that our diet includes optimal amounts of vitamins, minerals and other nutrients.

            Omega-3 fatty acids are absolutely essential for virtually every cell in the body. They are vital for normal development and function of the heart, brain, eye and skeleton. Numerous studies link omega-3 deficiency with behavior disorders, schizophrenia, bipolar disorder and attention deficit disorder, and other neuropsychiatric problems.

            Vitamin D also has numerous roles, especially in maintaining a vigorous immune system. The deficiency of this vitamin in childhood results in rickets, a softening of the bones, often accompanied by serious brain damage. It is one of the many nutrients that are essential in preventing osteoporosis in older persons.

            Both of these nutrients are lacking in most Americans. An astonishing 95 percent of children and more than 65 percent of adults have an inadequate dietary intake of omega-3s. More than half of adolescents and adults have inadequate levels of vitamin D, especially in the northern latitudes. These two nutrients together act in the synthesis of serotonin, a brain chemical that regulates executive function and social behavior.

            Psychiatric disorders in our young population have reached levels that threaten to overwhelm our healthcare system. Children’s hospitals throughout the country find themselves unable to cope with what is clearly an epidemic. Nutrition alone will not stem the tide but it clearly is one factor that is within our ability to improve. Perhaps we should start with some strategy to get our kids to bolster their diet with these synergistic supplements. 

Lifestyle

            We are about to see an assault on highly processed foods, which now account for 60 to 90 (!) percent of the Standard American Diet (SAD – a perfect acronym) There is more to this picture than the addition of dozens of chemicals that make non-nutritious foods so attractive and addictive. In the course of altering the basic ingredients, the manufacture of these products results in the loss of important vitamins, minerals and fiber. Sometimes these are added back in, of course. That may not be enough, as reported in data from the UK’s National Health Service, showing a surge in hospital admissions due to vitamin deficiencies.

            All three leading causes of death, heart disease, cancer and type 2 diabetes, are unequivocally associated with (a) a high intake of highly processed foods and (b) the lack of whole foods, such as whole grains, legumes, fruits and vegetables. Highly processed foods include our favorite processed meats: cold cuts, hot dogs, bacon and sausage. We might add a warning from a 2009 article in the British Journal of Psychiatry: Persons who ate whole foods had a 26% lower risk of depression; those who ate processed food had a 58% higher risk. (Akbaraly TN et al., Dietary pattern and depressive symptoms in middle age, Br J Psychiatry 2009 Nov;195(5):408-13)

Carvings April 1, 2025

No April Fool: It’s time to put an end to nutritional pornography.

            In a few months we will reach the end of the first quarter of the 21st century with no end in sight of the three epidemics that threaten to overwhelm our health system and our economy: obesity, type 2 diabetes and osteoporosis. The first two were almost non-existent at the beginning of the preceding century. The obesity rate in 1900 was approximately 5 percent; it is now 42 percent. Diabetes was almost entirely type 1, the juvenile form, a totally different disease from type 2 diabetes. The latter now affects 12.2 percent of the general population, more than one-third of people over the age of 65 and increasing numbers of children below the age of 18, some as young as six years! Type 2 diabetes was so uncommon in the pre-World War One era that it wasn’t clearly distinguished from type 1 diabetes until the 1950s.

Osteoporosis, the Third Epidemic, is going to crash down on us with a vengeance in about 30 years, as today’s young people fail to build a strong skeleton during the bone-building window between ages five and twenty-five. They transport themselves on electric bikes, scooters and skateboards, and replace childhood sports and games with screen-watching, eliminating the muscle stresses that nature intended to form a strong skeleton.  

            Someone recently sent me an insightful post: “Ninety percent of today’s supermarket food didn’t exist a hundred years ago. Neither did ninety percent of today’s diseases. Think about that.”

            Government edicts will determine what supermarkets will offer us in the coming decade. Trans fats have already been outlawed. Food coloring restrictions are imminent; the sugar content of processed foods is probably next; saturated fat and salt mandates will reach us in a few short years. SNAP (welfare) recipients are not allowed to use those funds to purchase alcohol or tobacco. It’s likely that they will see junk food added to that list during the current administration. Legislation is pending now in Tennessee to disallow the purchase of candy and soft drinks with SNAP funds. Other states will follow suit, and so will the federal government.

Carvings July 15, 2024

In the news

Increasing rates of colon cancer in young persons

          In less than a generation – from the year 2000 to 2023 – the incidence of colon cancer in persons below the age of 40 has doubled or tripled in some parts of the world. Colon cancer is one of the most common forms of cancer, not far behind number one, lung cancer. Three main causes of this increase have been emerging in the past few years: increased sugar consumption, low intake of fiber, and taurine, an ingredient in energy drinks. All three are associated with disruption of the good germs that inhabit the large intestine, the site of colon cancer.

            A diet that is high in sugar and low in fiber tends to promote the growth of organisms that are linked to increased inflammation, a factor that increases the formation of cancer cells, and in addition increases the risk of heart disease, stroke, diabetes and osteoporosis. Younger persons have a high intake of energy drinks that contain taurine, an ingredient that further promotes the growth of bacteria that promote inflammation. Young persons also have an abysmally low intake of fiber. Instead of the recommended 10 servings a day of fiber-rich plant foods, the average teenager gets less than ONE serving a day, most likely to be iceberg lettuce, a nearly worthless “vegetable.”

            About half of the adolescent population consumes one or more energy drinks every day. This does not bode well for the health of our population by mid-century.

Lifestyle

Are you a food label reader? Two reasons why you should be.

            Some food manufacturers deliberately mislead buyers and they have government’s permission to do so. Perhaps the most egregious example is the deceptive listing of “sugar” to make it look like there’s not as much of it in that product as you might think.

            Food manufacturers are required to list ingredients in order of weight and if they listed the amount of sugar in many foods you might put them back on the shelf. So if they are allowed to list every different type of sugar in pastry, for example, each ingredient would be farther down the list and thus appear to be less detrimental to your health. For example, the nutrient label on a popular supermarket’s almond bear claw coffee cake contains the following TEN different kinds of sugar, each listed separately: sugar, almond paste (which contains sugar), corn syrup, fructose, dextrose (also known as glucose), sucrose, invert sugar (a mixture of glucose and fructose), cornstarch (which breaks down into sugar), maltodextrin and high-fructose corn syrup. Some manufacturers even list glucose and dextrose as separate entities, even though they are one and the same. Except for the relatively small amounts of fructose and glucose found in fruit, none of the other forms were part of the human diet until a couple of hundred years ago. Today the average American takes in approximately one pound of sugar a week – 57 pounds a year. Is it any wonder that more than 80 percent of Americans are either overweight or obese?

            When you pick up a loaf of bread you might think that anything with a brown color is more healthy than white bread. Not necessarily, unless whole wheat or whole grain flour is the only ingredient. The term enriched flour means white flour and some breads have both, suggesting a healthy choice, and there might be much more white flour than brown. On the other hand, the brown color might be due to the addition of molasses, caramel, coffee or cocoa.

            Learn to read labels. It’s not rocket science!

Carvings June 1, 2024

In the news

More confusing research

          The last thirty years or so have seen a surge in publications touting the benefits of omega-3 fats in preventing heart disease and stroke. There have been a few studies that claim no benefit, but almost none have stated that these nutrients can be detrimental to heart health. A recent study from the UK reported that persons with poor heart health did receive benefits from omega-3s but previously healthy persons had a small (6 percent) risk of developing atrial fibrillation, a heart attack, heart failure or stroke.

          Even though this was a large study involving more than 400,000 people, it was observational and did not show direct causation. The authors noted that a limitation of the study was the lack of information regarding the dose and type of fish oil consumed. Takers of fish oil were significantly more likely to be elderly, which could be a factor in more of them developing atrial fibrillation.

          Although healthy persons taking fish oil supplements were more likely to develop heart disease, they were less likely to die than non-takers. The authors’ discussion did not take into consideration other benefits of omega-3 fats, including the lowering of inflammation, reduction in blood pressure, improvement in immune function and a lower risk of sudden cardiac arrest. A circuitous benefit of omega-3 fats is their role in preventing osteoporosis. A fall in an elderly person that results in a fracture leads indirectly to death, especially when that fracture involves the hip or the skull, for very different reasons.

          In an associated commentary, a nutritionist stated that she still recommends an intake of 500 milligrams of omega-3 fats per day, from fish, fish oil or a combination of the two.

And so we come to sardines!

          Sardines are one of the most beneficial foods on the planet, but I can already hear you say “Ugh! Not for me!” From my lecture experience I am well aware that Americans are about evenly split between sardine lovers and sardine haters. An Internet search will come up with nearly 100 recipes for sardine dishes, although I will admit that “sardine pie” did not excite me.

          Because sardines are so low on the food chain there is virtually no risk of mercury contamination that is a challenge in large fish such as tuna. A single four-ounce serving provides more than the recommended amount of omega-3s mentioned above, a fourth of your calcium requirements and as much iron as a hamburger. Canned sardines are convenient, can be stored almost forever and are a whole lot cheaper than beef or larger fish.